Cambridge AssessmentInternational EducationSyllabusCambridge IGCSETMCombined Science 0653Use this syllabus for exams in 2025,2026 and 2027.Exams are available in the June and November series.Exams are also available in the March series in India.Version 1For the purposes of screen readers,any mention in this document of Cambridge IGCSECambridgerefers to Cambridge International General Certificate of Secondary Education.PathwayWhy choose Cambridge International?Cambridge Intemnational prepares school students for life,helping them develop an informed curiosity and alasting passion for learning.We are part of Cambridge University Press Assessment,which is a departmentOur Cambridge Pathway gives students a clear path for educational success from age 5 to 19.Schools canshape the curriculum around how they want students to learn-with a wide range of subjects and flexible waysto offer them.It helps students discover new abilities and a wider world,and gives them the skills they need forlife,so they can achieve at school,university and work.Our programmes and qualifications set the global standard for international education.They are created bysubject experts,rooted in academic rigour and reflect the latest educational research.They provide a strongresources.Our mission is to provide educational benefit through provision of international programmes and qualificationsfor school education and to be the world leader in this field.Together with schools,we develop Cambridgeleamers who are confident,responsible,reflective,innovative and engaged-equipped for success in theEvery year,nearly a million Cambridge students from 10000 schools in 160 countries prepare for their futurewith the Cambridge Pathway.School feedback:'We think the Cambridge curriculum is superb preparation for university.'Feedback from:Christoph Guttentag,Dean of Undergraduate Admissions,Duke University,USAQuality managementquality management system for the provision of intemational qualifications and education programmesfor students aged 5 to 19 is independently certified as meeting the intemationally recognised standard,ISO 9001:2015.Leam more at www.cambridgeinternational.org/ISO9001Cambridge Assessment Intemational Education is part of Cambridge University Press Assessment.Cambridge University PressAssessment is a department of the University of Cambridge.Cambridge University Press Assessment retains the copyright on all its publications.Registered centres are pemmitted to copyacknowledged to a third party even for internal use within a centre.ContentsWhy choose Cambridge International?...........1 Why choose this syllabus?52 Syllabus overview.…AimsContent overview9Assessment overview10Assessment objectives113 Subject content ..........................13Biology13Chemistry27Physics444 Details of the assessment60Core assessment60Extended assessment60Practical assessment61Language of measurement64Apparatus,materials and reagents65Safety in the laboratory71Electrical symbols72Symbols and units for physical quantities73Notes for use in qualitative analysis74The Periodic Table of Elements76Mathematical requirements77Presentation of data78Conventions (e.g.signs,symbols,terminology and nomenclature)80Command words81